Shoudn't the spirit generally best be served first, and followed up with a beer? thats how I prefer it (although not whiskey, I hate the shit)
Athough personally if I drink alcohols I prefer ales, or if for an intoxicant simply neutral pure ethanol, diluted to a safe concentration which won't burn with a flavoring of choice, lime cordial workets quite well, rose's or britvic's added to dilute it down to about 70% alcohol works.
I'd rather drink a ml or two of tertiary pentanol (otherwise known systematically as 2-methyl-butan-2-ol) or alternatively for a real wallbanger, 1-ethynyl-cyclohexan-1-ol. Tert. alcohols are superior both subjectively (IMO) in the way they feel in regard to the intoxicant properties and are likely healthier, at least in the case of saturated, non-halogenated alcohol, although the most potent are branched-chain tertiary chloroalkynols, for some reason the triple bond and halogen combination, such as in the sedative-hypnotic ethchlorvynol confers the most powefully intoxicant and more importantly, more qualitatively euphoric properties, as well as muscle-relaxing properties. But the saturated, nonhalogenated tertiary alcohols of medium chain length are likely the healthiest, the tertiary alcohols are not easily oxidized, whereas primary and secondary alcohols are, and get metabolized to aldehydes (in the case of primary alcohols) and some diols (glycols) although not all. And aldehydes are generally pretty rough on the body as a general rule of thumb, whilst sec. alcohols get metabolized to ketones, less unfriendly than aldehydes (compare say, propenal, acrolein to give it its common name, to acetone, and you'l get what I mean, athough unsaturated (double bonds that is, not so sure about metabolic fate of triple bonds in alcohols although I remember that 1-ethynylcyclohexan-1-ol is a pretty potent and irreversible inhibitor of some hepatic cytochrome-P450 series enzymes, IIRC its P450-3A4 mostly. But ene-als and enones can be HIGHLY toxic, above and beyond a simple saturated ketone or aldehyde. Acrolein is a simple enal, and the simplest of the enones, ketene, is frightfully lethal in very low concentrations. To the extent that I thought at one point to maybe make a ketene lamp (these generate ketene, ethene-one, via pyrolysis of acetone, and then lead it into glacial acetic acid to produce acetic anhydride, generally by passing acetone over an electrically heated wire filament, but got as far as reading of the properties of ketone in the pre-study phase and then thought 'bugger that well off, I don't want to die, nor do I want the neighbors to drop like flies in the wake of my own corpse'
