« previous next »
Pages: 1 ... 299 300 [301] 302 303 ... 877   Go Down

Author Topic: What have you done today? (Pt 2)  (Read 212382 times)

0 Members and 4 Guests are viewing this topic.

Offline odeon

  • Witchlet of the Aspie Elite
  • Webmaster
  • Postwhore Beyond Repair
  • *****
  • Posts: 108944
  • Karma: 4483
  • Gender: Male
  • Replacement Despot
Re: What have you done today? (Pt 2)
« Reply #4500 on: December 22, 2013, 04:13:42 AM »
Quote from: Parts on December 20, 2013, 06:42:37 PM
I broke a light bulb with my head at work :tard:  I was on my stilts and stepped backwards hitting it with the back of my head, at least it wasn't on ,  and no it wasn't the first time this has happened  :LOL:

:laugh:

Logged
"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."

- Albert Einstein

Offline Lestat

  • Pharmaceutical dustbin of the autie elite
  • Elder
  • Obsessive Postwhore
  • *****
  • Posts: 8965
  • Karma: 451
  • Gender: Male
  • Homo stercore veteris, heterodiem
Re: What have you done today? (Pt 2)
« Reply #4501 on: December 22, 2013, 09:02:44 AM »
Read, read more, and more other stuff.

Came up with a bit of a novel idea for making alpha-substituted tryptamines from tryptophan

(Hell-Vollhard-Zelinzki rxn using catalytic PBr3, mol. eq. Br2 to halogenate the alpha position of tryptophan (or 5-HTP if serotonin analogs were aimed for, or more interestingly, alkylate that hydroxyl first on 5-HTP), followed by displacement of halide by a tosylate ester, such as, for ex. AMT, methyl tosylate, then decarboxylation of the tryptophan to (alpha-alkyl)tryptamine.

Methyl tosylate is pretty poisonous stuff, but then again, it wouldn't be a good idea to breathe/get splashed by Br2 or phosphorus tribromide either. Although probably much less likely to prove lethal.

I think it should work, certainly plan to give it a shot. I love AMT, cracking psychedelic/entactogen material for me personally, although some people find it rough, and its known to be a bit of a gutbuster for many especially at higher levels. Quite variable as to peoples response to dosage also, but for those who it seems to agree with, seems to be well liked.
Logged
Beyond the pale. Way, way beyond the pale.

Requiescat in pacem, Wolfish, beloved of Pyraxis.

Offline odeon

  • Witchlet of the Aspie Elite
  • Webmaster
  • Postwhore Beyond Repair
  • *****
  • Posts: 108944
  • Karma: 4483
  • Gender: Male
  • Replacement Despot
Re: What have you done today? (Pt 2)
« Reply #4502 on: December 22, 2013, 03:17:23 PM »
Swept floors and did some general dusting of things. Watched an episode of Cosmos and realised the world desperately needs a new Carl Sagan. Posted here.
Logged
"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."

- Albert Einstein

Offline Parts

  • The Mad
  • Caretaker Admin
  • Almighty Postwhore
  • *****
  • Posts: 37477
  • Karma: 3062
  • Gender: Female
  • Who are you?
Re: What have you done today? (Pt 2)
« Reply #4503 on: December 22, 2013, 06:14:24 PM »
Did some deep cleaning around the house since everyone was out for the day
Logged
"Eat it up.  Wear it out.  Make it do or do without." 

'People who say it cannot be done should not interrupt those who are doing it.'
George Bernard Shaw

Offline Lestat

  • Pharmaceutical dustbin of the autie elite
  • Elder
  • Obsessive Postwhore
  • *****
  • Posts: 8965
  • Karma: 451
  • Gender: Male
  • Homo stercore veteris, heterodiem
Re: What have you done today? (Pt 2)
« Reply #4504 on: December 22, 2013, 07:28:31 PM »
Bah I derped with my idea. Amine would need protecting certainly. And given the mechanism of the Hell-Volhard-Zellinski, Not sure if it would be amenable to protect the amine prior to reaction, amongst other things.

I need to dig out my ebooks on protecting groups and do some digging, and some scheming.
Logged
Beyond the pale. Way, way beyond the pale.

Requiescat in pacem, Wolfish, beloved of Pyraxis.

Offline "couldbecousin"

  • Invincible Heisenweeble of the Aspie Elite
  • Elder
  • Postwhore Beyond Teh Stupid
  • *****
  • Posts: 53577
  • Karma: 2716
  • Gender: Female
  • You're goddamn right.
Re: What have you done today? (Pt 2)
« Reply #4505 on: December 22, 2013, 08:41:42 PM »
  I replaced three lightbulbs in my apartment with the energy-efficient ones my boss gave me.  :thumbup:
Logged
"I'm finding a lot of things funny lately, but I don't think they are."
--- Ripley, Alien Resurrection


"We are grateful for the time we have been given."
--- Edward Walker, The Village

People forget.
--- The Who, "Eminence Front"

Offline Queen Victoria

  • Ruler of Aspie Universe
  • Elder
  • Almighty Postwhore
  • *****
  • Posts: 28244
  • Karma: 2805
  • Gender: Female
Re: What have you done today? (Pt 2)
« Reply #4506 on: December 22, 2013, 08:55:09 PM »
This week I had to do some frenetic re-arranging of piles to have the new TV and internet access installed.  I set a goal that by tomorrow I would go through the 3 clothes baskets I put by PA's bed.  Accomplished.  Result: trash and thrift store donations were accumulated.

Had a clearing of the air after a bit of a tiff with PA. 
Logged
A good monarch is a treasure. A good politician is an oxymoron.

My brain is both uninhibited and uninhabited.

:qv:

Offline "couldbecousin"

  • Invincible Heisenweeble of the Aspie Elite
  • Elder
  • Postwhore Beyond Teh Stupid
  • *****
  • Posts: 53577
  • Karma: 2716
  • Gender: Female
  • You're goddamn right.
Re: What have you done today? (Pt 2)
« Reply #4507 on: December 22, 2013, 08:56:03 PM »
Quote from: Queen Victoria on December 22, 2013, 08:55:09 PM
This week I had to do some frenetic re-arranging of piles to have the new TV and internet access installed.  I set a goal that by tomorrow I would go through the 3 clothes baskets I put by PA's bed.  Accomplished.  Result: trash and thrift store donations were accumulated.

Had a clearing of the air after a bit of a tiff with PA.

  Clearing space and clearing the air, a day well spent.  :thumbup:
Logged
"I'm finding a lot of things funny lately, but I don't think they are."
--- Ripley, Alien Resurrection


"We are grateful for the time we have been given."
--- Edward Walker, The Village

People forget.
--- The Who, "Eminence Front"

Offline odeon

  • Witchlet of the Aspie Elite
  • Webmaster
  • Postwhore Beyond Repair
  • *****
  • Posts: 108944
  • Karma: 4483
  • Gender: Male
  • Replacement Despot
Re: What have you done today? (Pt 2)
« Reply #4508 on: December 25, 2013, 10:08:59 AM »
Watched several episodes of Sherlock Holmes with Jeremy Brett starring in the title role. Brett's is the finest Holmes to date, IMHO.
Logged
"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."

- Albert Einstein

Offline Pyraxis

  • Werewolf Wrangler of the Aspie Elite
  • Caretaker Admin
  • Almighty Postwhore
  • *****
  • Posts: 16680
  • Karma: 1433
  • aka Daria
Re: What have you done today? (Pt 2)
« Reply #4509 on: December 25, 2013, 10:36:07 AM »
Watched Christmas movies with WolFish while eating ham and cornbread.
Logged
Quote from: Gopher Gary on October 11, 2015, 06:41:29 PM
You'll never self-actualize the subconscious canopy of stardust with that attitude.

Offline Gopher Gary

  • sockpuppet alert!
  • Maniacal Postwhore
  • *
  • Posts: 12683
  • Karma: 652
  • I'm not wearing pants.
Re: What have you done today? (Pt 2)
« Reply #4510 on: December 25, 2013, 11:21:26 AM »
I did a Merry Christmas!! :GA:
Logged
:gopher:

Offline Queen Victoria

  • Ruler of Aspie Universe
  • Elder
  • Almighty Postwhore
  • *****
  • Posts: 28244
  • Karma: 2805
  • Gender: Female
Re: What have you done today? (Pt 2)
« Reply #4511 on: December 25, 2013, 12:17:39 PM »
Now that we have BBC America, I'm Dr. Whoing  Dr. Who.

Translation - since you have to take DW as you find him, rapid speech with the occasional heavy accent and convoluted story lines, I just watch him for enjoyment.  I'm able to get 10 or 15 minutes or more here and there and just enjoy.
Logged
A good monarch is a treasure. A good politician is an oxymoron.

My brain is both uninhibited and uninhabited.

:qv:

Offline Semicolon

  • The Punctuated Equilibrium Of The Aspie Elite
  • Elder
  • Insane Postwhore
  • *****
  • Posts: 12344
  • Karma: 693
  • I am an echolalic mastodon.
Re: What have you done today? (Pt 2)
« Reply #4512 on: December 25, 2013, 08:58:48 PM »
Quote from: odeon on December 25, 2013, 10:08:59 AM
Watched several episodes of Sherlock Holmes with Jeremy Brett starring in the title role. Brett's is the finest Holmes to date, IMHO.

:orly:

Better than everyone else on this list? :nerd!:
Logged
I2 has a smiley for everything. Even a hamster wheel. :hamsterwheel:

Quote from: iamnotaparakeet
Jesus died on the cross to show us that BDSM is a legitimate form of love.
Quote from: DFGL on October 20, 2013, 05:15:22 PM
There is only one truth and it is that people do have penises of different sizes and one of them is the longest.

Offline Parts

  • The Mad
  • Caretaker Admin
  • Almighty Postwhore
  • *****
  • Posts: 37477
  • Karma: 3062
  • Gender: Female
  • Who are you?
Re: What have you done today? (Pt 2)
« Reply #4513 on: December 25, 2013, 09:46:08 PM »
Had company over then went to my sisters
Came home and had more people over
 :GA: :GA: :GA:
Logged
"Eat it up.  Wear it out.  Make it do or do without." 

'People who say it cannot be done should not interrupt those who are doing it.'
George Bernard Shaw

Offline odeon

  • Witchlet of the Aspie Elite
  • Webmaster
  • Postwhore Beyond Repair
  • *****
  • Posts: 108944
  • Karma: 4483
  • Gender: Male
  • Replacement Despot
Re: What have you done today? (Pt 2)
« Reply #4514 on: December 26, 2013, 04:29:56 AM »
Quote from: Semicolon on December 25, 2013, 08:58:48 PM
Quote from: odeon on December 25, 2013, 10:08:59 AM
Watched several episodes of Sherlock Holmes with Jeremy Brett starring in the title role. Brett's is the finest Holmes to date, IMHO.

:orly:

Better than everyone else on this list? :nerd!:

Well, of the ones I have seen, yes.
Logged
"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."

- Albert Einstein
Pages: 1 ... 299 300 [301] 302 303 ... 877   Go Up
« previous next »