Never tried ethylmorphine. I don't think its used here in the UK at all.
No need to try a codeine analog, except as a curiosity-driven bioassay. When I can have morphine itself. Just harvesting enough pods and poppy straw at the moment to make it worth an extraction and separation of the morphine, codeine, thebaine and other alkaloids. I want to try a purified version of 'kompot', aka polish heroin. Basically they just acetylate a crude mixture of alkaloids derived from pod tea, evaporated down etc.
Although I will be separating out the purified alkaloids, removing the codeine content for future experimentation, as codeine can easily cause fatal pulmonary oedema if shot up, thanks to it being such a bugger when it comes to releasing histamine.
And rather than the traditional acetic anhydride/acetyl chloride to prepare mono/di-acetylmorphine, aka H; the plan is to hit it with some of my spare acetyl chloride, as far as my AMPAkine project goes, I have tons of the stuff spare, I only need a few mililitres, and I have 100ml or so. The AMPAkine I'm working on, DM-235, otherwise known as sunifiram, is fully active in the 0.001mg/kg range in rats, so presumably less in humans due to far faster murine metabolism; compared with humans. IIRC the human metabolic rate is in the region of one tenth of the murine model; 10mg of given compound XYZ compound in the rat, is not unlikely to equate to around 1mg of XYZ intravenound XYZ in man. Just a rule of thumb however, and certainly not consistent enough to use t as anything more than a tool to work doses out, just using that rule of thumb and banging up whatever it says is likely in people could easily lead to an overdose/fatality.
All the morph/codeine/opium tincture syrups here are basically ancient throwbacks to a past era, but still, its good to be able to just walk round town and pop into every pharmacy and supermarket to get my goodies. My favourites are Gee's linctus, a tincture of opium in a spicy flavoured cough syrup. Very much prehistoric and hard to find these days though
and codeine linctus which is likewise fucking hard to find. No rx needed, but few pharmacies carry it now, There are three of the latter, one flavoured with sugar free orange. Cunting well rank stuff, it tastes exactly the same as the penicillin liquid I was forced to continue taking despite being allergic to beta-lactam antibiotics. If they did that now,it would kill me..truly horrid stuff. The others are the non-sugar-free one, which is flavoured with, of all the crowbegotten things, chloroform. I LOVE the scent of chloroform I make a cocktail with it; lol. Equal parts of tesco own brand lime juice, the codeine syrup, and vodka. Tastes great, if I do say so myself:P
The last is terpin and codeine linctus. Fucking well foul stuff, contains white pine oil, its absofuckinglutely awful. contains a wee little bit more codeine than the others, just 1mg/ml though though; irritate my stomach though, I can't take more than a shot glass of it at one time though, to avoid throwing up.
At the same time, not necking more than half a bottle or so,to avoid G.I discomfort. More than I can tolerate of terpin&codeine at any rate. Mein Gott! that stuff is bloody foul!
I'm looking forward to reaching my target for pod harvesting-minimum=1kg of pods. Preferably at least 1.5kg. So I can extract repeatedly with acidified H2O, filter the plant matter out of it, denature any proteins with methanol, distill off the solvent, then get shot of any solvent remaining in the mixture. Purify by forming the calcium phenolate salts, which are insoluble in H2O, then extract the codeine, for future experimenting or other uses, ,which could well cause anaphylactic shock and death, then simply taking up the alkaloids in methanol (best alcohol to use for me, as I have about 10 liters just sitting there on its arse in one of the cupboards in the lab I keep my reagents and solvents in. Take some propionyl chloride up in thoroughly dried toluene, then add the two, reflux in the 50ml flask I've been dying to try out for ages. Result? a full-spectrum (minus the codeine and its pulmonary oedema-causing tendencies, and the propionyl esfters of any phenolic alkaloids present, such as morphine. Dipropionylmorphine is at least twice and a bit as potent as skag itself, and more lipophilic (fat soluble) so it hits faster and gives a greater rush when IVed.
Needs micron filtering of course before use.
Can't wait to try it out:).
