Gracias, just what I could do with now. Its near hot enough to take a bath in THF or ether just so I could stand in front of a fan and try to turn myself into a fucking snowman by evaporative cooling, with the advantage that if it didn't work, I'd at least wake up several hours later, although making sure to stay about a mile upwind from the tiniest spark.
*packs a fresh pipe with a goodly sized chunk of H powdered and stuffed in there like a useful version of donald trump, only trying to squeeze into a toddler's romper suit (well it would suit the bugger :spazz:)*
Just make sure to heat the outside, until it melts first, otherwise you'll suck dust bits and worst comes to worst cough back up the pipe (yeah, I admit it, I did that once, although thankfully I'd gotten a 20 bag, and stuffed a chunk down there, without too much dusty powdery bits, shot all over the show, was in a bit of a stress and exhausted from walking across most of the city, as the exhausted and distinctly peeved autie flies, so to speak :spazz:), and hold it in as if you thought yourself about to drown.
Have to make do with some which has yet to be personally tasted, but its from the same individual who vouches for the same batch, and he isn't a dealer, or working for one, he's had it and rates it highly, just that the order was for a quarter oz, and it arrived as a pair of 8ths, as for its pedigree, so to speak, the vanishing act down to the last foil plus an analytical sample's worth for GC-MS and NMR analysis that the first bag of the batch pulled, can speak for itself. Early morning yesterday to early morning today...hello...nice knowing you...smell ya' later (when the last bits are vaped from the pipe re-condensate and the foils with a few melted patches), which would be, bar the sample for analysis and tracking purposes, and a last pipe before I take a kip, once I've finished doing some reading of some research journals which have more than piqued my interest, based on hypervalent iodine chemistry.)
But no worries, this'll be a fair trade alright
Got me finding myself somewhat stimulated with lower (for me) doses, and after an IM shot, having converted the freebase to the water-soluble citrate salt, I'm finding myself nodding off.
Did end up taking the sleeping pill I was debating whether or not to take sometime mid morning, although still dark, something like 6am, (nitrazepam) and put it off, reading the journal articles and ebooks, and accordingly setting a plottin' and a schemin'.
Having in mind (once one has the oxime of course), the possibility, of, in place of the rather rough and touchy hypochlorite bleach based hoffmann degredation (converts an amide to a primary amine one carbon shorter in the chain length, known amongst bees for its utility in converting the beckmann rearrangement product of the aldoxime derived via reaction of hydroxylamine plus a gentle base, such as sodium acetate, or carbonate of potash, into MDA, the primary amine (nor-MDMA basically, chop off that methyl group on the amine and one has MDA, a little more potent by weight, but more actively visual and closer to psychedelic effects along with its entactogenic effects). Usually, its done with bleach, I.e the combination of sodium hypochlorite and an alkali metal hydroxide base, which household bleach conveniently comes as, although better yields are to be had by preparing it fresh from the requisite amount of chlorine gas piped into (cold, if hot, it gives chlorate instead) aqueous sodium hydroxide (lye), so as to form the desired (slightly in excess) quantity of NaOCl and leave enough NaOH behind to form the solution to be used in one go rather than mucking about doing it separately and combining them)
Goes from helional, to the aldoxime, beckmann rearrangement to the amide, then deprotonation of the amide, halogenation to form an N-haloamide which is somewhat unstable, and through an isocyanate (which are in general, especially volatile ones, the smaller the more volatile and the worse the potential, but they are seriously unstable, and degrade as fast as they are formed in aqueous or other protic media, forming amines with loss of CO2 in H2O, and if alcohols are present or used as a solvent, then the isocyanate does the same thing, reacting to form the carbamate of the alcohol from the corresponding amine the isocyanate would otherwise form in H2O. This one is, in terms of molecules, heftyish and not anorexic, skinny and as such highly volatile, like something small and gaseous, such as the methyl isocyanate which got released in masse and after slithering its way towards the indian city of Bhopal, caused one of the most thoroughly notorious industrial disasters, making a pretty determined effort to wipe the place clean of anything that intakes fuel and craps out waste, procreates and breathes air, aside from fire. Didn't sterilize the entire city but caused mass casualties. Thankfully the helional routes, although going through an isocyanate are not ones which involve as the penultimate product, a tiny, vicious little bastard like the methyl and other gaseous lower alkyl isocyanates. Bigger the better, or at least the less vile, and when generated in water, they react to form the amine that all that comes off is carbon dioxide and solvent fumes to be trapped or piped outside and burnt.
Think akin to dogs. Those tiny little fuckers, the smaller they are the worse the temper they have on them. Isocyanates are similar, only they have much sharper teeth. But the bigger they are the less volatile and so less ability to go where they could cause trouble. I've got a 4 gallon drum of 4,4-diphenylmethyldiisocyanate in the garden for example, for polymer chemistry (making glues and resins basically) and it isn't about to jump up and bite me in the nackers, I'd still wear a gas mask and gloves if I opened it, but its viscous, thick as fridge-cold just-mixed epoxy glue almost. Would sure as hell not take a sniff, but its big enough not to have a vapor pressure that means it can come and turn my lungs into polymerized plasticized, cross-linked models of a respiratory system, either)
Alternatively (all the hoffmann degradations go via the isocyanate, its not that I'm trying to avoid, its harsh conditions, and this hypervalent iodine as oxidant version, is interesting as both hypochlorite and the TCCA (trichloroisocyanuric acid) variant, apparently higher yielding, although I've never performed it myself) use strongly basic conditions, whilst the hypervalent iodine potential route, IF it can work as intended, could both perform the Beckmann rearrangement of oxime to amide, and the Hoffmann degradation of amide to product MDA in a single reaction, under acidic conditions.
AFAIK, it hasn't been done, or if it has, people haven't talked of it. Either way its different enough to get me wondering.
And another potential oxidant, lead tetraacetate, again has me wondering too, known to effect Hoffmann degradations, but HOW, given the intermediacy of an N-haloamide...I've got plenty on my plate, methinks as far as studying goes. The hypervalent iodine oxidant in acidic (possibly a mixture of trifluoroacetic acid and peroxytrifluoroacetic acid) medium has most certainly caught my interest and then some. Never heard of the Hoffmann degradation taking place in anything but acidic systems)
