The only crime associated with tossing grenades into a cop shop, or shooting one up is if someone gets caught doing it. Oh, and missing shots. Unless of course someone is intending not to kill the pig they have in their crosshairs, but rather to inflict a wound of the kind that will leave them crippled and in agony for the rest of their filthy lying donut scoffing days, until all that donut fat atrophies away due to being confined to a wheelchair and fed through a tube in the stomach, or at least the bits of it that shotgun blast didn't spatter liberally over the nearest wall, and they waste away and die slowly and miserably.
Fucking bastards.
As for gangs in the likes of appalachia, I'll bet there are plenty of meth ops, although with tighter restrictions on PSE (not sure what the local state regulations are in that particular state with regards to PSE and eph) I doubt they could come close to competing with the mexican cartels, and if making in bulk it'd not be the D-meth from eph/pseudo reductions, but racemic product via reduction of P2NP made via knoevanagel condensation.)
Thats the kind of thing, producing for self use and local distribution though thats likely to come as a consequence of deprivation, social inequality. And the folks slinging the crystal are going to be wanting to protect their interests, likely as not at the end of a gunsight.