The life-strategies of amphibians are a bit different from lizards. They're mostly adapted for colder temperatures, so they don't have the comparatively high metabolic rate of a lizard that's been basking in the sun, and instead of having claws, teeth, scales and the ability to quickly escape from predators, they rely on hiding, being nocturnal and having toxic glands in their skin, often with warning colouration, either all over the body or just on the belly. The ones that just have warning colours on their belly have an
unken reflex where they show off their underside when threatened. Some of them will roll over and play dead, too.
They also have much less sturdy and less well developed skeletons than lizards that don't provide much in the way of attachment points for muscles and wouldn't stand up the forces of large, powerful muscles acting on them. Here's a skeletal comparison: