Not a good idea!
Insertion up one's muff that is, changing the PH balance up there will make it more suitable environment for an infection to take hold.
Plugging (stuffing it up the arse in solution is a viable mode of administration, never stuffed MDMA up there myself, not a big fan of it to begin with)
I am not a big stimulant fan, its take it or leave it with me. They can be useful sometimes, functionally speaking, but in general, not my thing.
Currently experimenting towards a test of the propionyl ester of loperamide (aka immodium)
12mg loperamide, as the hydrochloride salt, suspended in 10ml or so of anhydrous toluene, a dash of anhydrous sodium carbonate to suck up the formed HCl, and 0.5-0.75ml or so of propionyl chloride.
Loperamide is actually a POTENT opioid, apparently, although a neurotoxic one, damaging dopaminergic neurons. I know of people who have tried the ester though with success. I sure wouldn't want loperamide itself up there, but yes, its a potent opioid, it just doesn't cross the blood-brain barrier in significant quantities. But its possibly on a par, potency speaking, with fentanyl. I do hope so
I think I'll let it spin on the hotplate/mag stirrer for another 15 minutes or so, then evaporate off the solvents and excess halide, see what happens. just a really halfarsed trial really, not sure if it will be successful, but hey....thats what happens when speshul ed people get bored