Gahh...just having one relatively minor, although fucking annoying problem with my increased dose of oxy. Should have thought to have my doc give me an increased dose of antihistamines to go with it, to counteract the itching caused by histamine release.
Already on two different ones, fexofenadine, a relatively long acting, nonsedating one, and chlorphenamine, an intermediate acting sedating antihistamine. But the OC 80s are a bit more than the dose of both put together can handle; and particularly so since one of my other meds, that I take to prevent myoclonus/myoclonic seizures also causes some histamine release.
Shouldn't be a problem though getting my doc to give me some more antihistamines.