Well she can tell him, if he has the sheer GALL to get pissy with her if she missed a funeral because HE couldn't be fucking bothered to look at the damn text she sent him; that he has nobody but himself and his own lazy bitch arse to blame for being a bone idle piece of crap, and to go and drink bleach, y'know, just because it's the right thing to do. Maybe that he also, as an afterthought post-script, ought to go fuck himself. At least he'd be familiar with the concept, sounds like he spends most of his life with head up sphincter.
My quick bitch-thats the second time today I've had a sudden bout of severe nausea. First time, I was sitting on the sofa, eating a bowl of chili con carnage (my old man did it, and it isn't chili con carnE, unless there is fly agaric and peppery boletus in there as seasonings), watching star trek; when all of a sudden, went from feeling completely fine, to having that revolting 'Ulch!!' sensation trying to rip it's way hand over hand up from my duodenum until it's gotten up to the throat and feels as though a kidney is poised to taking a running jump for freedom by way of both nostrils (just one kidney, but both nostrils). Was fine one moment, and in the time it took go go from normal to knowing for sure that I was going to puke within moments if I didn't do something about it, was just the time it took for spoon to emerge from bowl and get half way to my mouth, before I got the message, and tore off upstairs to get a needle-less measuring syringe, grabbing a bottle of cyclizine tablets on the way up off the lounge coffee table and a glass bottle to crush them with.
Got upstairs, somehow restraining my guts, and was right at the stage where the saliva filling one's mouth feels hot for no apparent reason, when I managed to squirt a syringe full of water into a little plastic measuring cup, with 4 cyclizine tablets in it, powdered and crushed with the bottle, so it could be dosed...well, the only other place than his mouth that a man has, that a syringe with no needle is generally used with medical purposes in mind.
That way, it can't be puked up before it can go to work, and works within a minute or so. SOMEHOW, I managed to do it, and keep my insides, well, inside me.
Suddenly just happened again a few minutes ago. Only this time ended with insides being outside; down the bog sink in particular. Did manage to get 2 cyclizine tabs powdered and liquid added, in me, but unfortunately still had to dash for the crapper, only made it as far as projectile spew range, but at least managed to keep it dead on target into the sink. Dosed another 2x cyclizine tabs since I'd just swallowed two and had two up north, and the swallowed pair were taken literally tens of seconds before throwing up, so will have come right back up and out.
And this time, I've had the forethought to prepare a 4x50mg/5ml solution, ready for use in case it happens again, so there is no waiting time trying to hold my innards in whilst having to move to make the solution for non-oral, needle-free dosing, so its ready there to use without moving more than an arm.
No idea what caused it, either time. Just hit me all of a sudden, one minute not sick, the next feeling nauseated as hell and about to blow chunks. Both times, really sudden onset, absolutely no warning. I am SO glad that I wasn't either sitting down to drop a deuce, or taking a leak and in mid-squirt at the time. Think I'll take a couple of ondansetron tablets too (anti-barf pills of near enough weapons-grade for those really intractable heaves when nothing else will do the job properly, although the cyclizine is really effective and powerful [its a strong sedating antihistamine with antimuscarinic effects, and an extremely potent antinauseant and antiemetic,] whilst ondansetron does the same job without acting either on cholinergic or histaminergic receptors, working instead by binding to serotonin receptors, of the 5HT3 subtype, as a strong 5HT3 receptor antagonist, with 5HT3 receptor activation being very strongly correlated with nausea and vomiting.
Its found mostly in the peripheral nervous system, especially in high expression levels within the stomach and gut, although 5HT3 is also expressed in the CNS, such as within the brain stem, and linked with, on activation, increased seizure tendency, nausea and anxiety, whilst it's activation causes physical vomiting, stimulation of pain-related nerve pathways and overall, increased sympathetic tone.
All in all, a little bastard of a receptor. But potent antagonists of 5HT3Rs such as ondansetron do the opposite, and are as a result, very, very effective antiemetics and antinauseants. So going to pop a couple of those, as an insurance policy, so to speak, so if when the cyclizine wears off I have another sudden bout of 'ohfuckgeddoutathegoddamnwayyousonOfAbiIIIIIIItttCHhh!', it'll help lower the tendency to puke long enough for the readymade measuring syringe of cyclizine solution, mixed in with my next dose of oxycodone IR to make sure I can't throw that up.
Would have added the chlormethiazole I take for seizure control to the mixture, but unfortunately, I had to make do with swallowing it after the cyclizine I had just before took effect, after I'd thrown up and washed the sink free of chunks of mushrooms, half-digested kidney beans and stringy bits of minced fried beef, plus the odd odd reddish-orange gelatinous, amorphous blob of something that it seems, was, at one time in the recent past, of a tomato-based origin here and there come back to haunt me.
Couldn't add the chlormethiazole to the ready-prepared mixture, because chlormethiazole freebase attacks and dissolves plastics into goo, like pouring nail varnish remover (acetone) onto polystyrene foam. So it would melt both the plastic measuring cup, the barrel of the syringe, and weld the inside of the barrel to the plunger. And I don't much fancy either wasting the antiseizure meds, or pain meds for that matter, having liquefied plastic up my arse; that just can't be good for you
Damn insides. They hate me. And the feeling is mutual. No warning at all this time, and absolutely no idea why, nor is there any good reason for why me chit'lins to make a desperate attempt to secede from the fatherland. So yeah, I really don't need both nausea AND an anal sphincter shrinkwrapped on the INSIDE which can blow bubbles of air-setting solvated polymer out of my arse, twist them around at the end , poke a pin through it and light a match to send them flying on a current of flaming methane and hydrogen sulfide. Come to think of it, I don't need a polymer film-coated rectum WITHOUT feeling nauseous. Or feeling nauseous without a teflon backside-starfish; either.
