Depends. Will say hello or something like that at least.
In a bigger city where I have to be now and then, I meet lots, and I will say hi or something like that. Funny, I think they know me by now, they hardly ever ask me for something. Would they, and I would have some change, they'd get some.
Here in the village, only once in a blue moon, there is a homeless person selling a homeless magazine at the supermarket. Certainly in the beginning, I was sure that their bus ticket to get here was more expensive than the amount of money I had to do groceries. So, just a hello was what they'd get.
I feel no need to ignore people who are homeless. I know it is very easy to get to that stage.