John Best is apparently looking for a cure for his son's autism, and is using Chelation therapy on him to get it. Anyone who tells him it's a load of shit gets a mouthful of abuse.
Shrek is a fat bastard who is very religious and he keeps crapping on about trying to get girls, but his standards are too high. Then he whinges when no-one wants to go out with him because of his bigotted views. Sort of a 40-ish version of Judy.