Yes, along with some AP-237. Wondering if AP-237 could better be made in a batch process, acid-base extracting the amino-amide product, and then decarboxylating 1,4-bispropionylpiperazine by prolonged boiling in strong lye solution to recover the piperazine that didn't end up as the desired product, since the 1,4-bis-amides won't follow through in an acid-base extraction because amides are not very basic, and unlike amines, won't form freebases soluble in nonpolar solvents if there are no other functional groups that themselves will follow in an a/b.
That, and I've been looking at the potential of trivalent cerium as a catalyst. I've heard reports of 99% 1-acylation of piperazine hexahydrate with negligible formation of 1,4-bisacylated byproducts which is damn impressive. Also heard tell of excellent results using divalent copper, CuCl2 in particular, as well as Cu (I) salts [Cu(II) are the cupric salts whereas Cu(I) are the corresponding cuprous salts. No cerium compound on the lab shelves but can easily obtain them, and copper (II) chloride I definitely have, got a big flask of the solution, and all I'd need do is evaporate it, and possibly treat it with Cl2 gas and heat or with thionyl chloride if the anhydrous salt is needed.
