No, they even make 'em in .357 and .41 Magnums.
Don't forget .440 Corbon, a .50AE cartridge necked down to take a .44 bullet. From what I understand it shot really flat but it never caught on with the long range metallic silhouette crowd so it was discontinued. Now we have the .460 S&W to play with, now
that's a flat shooting cartridge for a handgun.
To answer the other posts, here's me with the DE:
I was doing a
Miami Vice-esque Halloween costume that year, and a big flashy gun seemed appropriate. Yes, I still have it...